July 19, 2019

Congratulations Emma!

Congratulations to our awesome Y3 project student Emma who graduated with First Class honours. She did some great work in the lab and will be starting her PhD in London to work on a topic near and dear to our hearts - the biology of MDS! Good luck Emma, we'll miss you but we will see you at ASH in 2022! 

May 28, 2019

Calreticulin in Canada

Edwin attended the 2019 Calreticulin Workshop in his sorta-hometown of Montreal, Canada to discuss some of the lab's work on calreticulin. It was a great meeting and was a chance for basic biologists to mingle with clinician-scientists to talk about all manners of things related to calreticulin (as well as other fun topics like pooping tardigrades!). Looking forward to the 2021 Workshop in Loire, France!

May 17, 2019

Jeanne wins speaker prize at the Leeds Postgraduate Symposium

A successful Leeds postgraduate symposium. Congrats to Jeanne who won one of the 3 speaker prizes for 3rd-year students for her great oral presentation describing the role of mutant CALR in MPN pathogenesis. Ghadah and Dom also presented their research as posters. Well done to everyone for their contributions!

January 18, 2019

Inaugural Yorkshire Myeloproliferative Neoplasms Symposium

MPN meets the North! Jeanne, Ghadah and Edwin (along with former lab technician and forever lab friend April) traveled to Sheffield for the inaugural White Rose Yorkshire MPN Symposium organised by Dr. Sally Thomas at Sheffield Medical School. There was lots of exciting science shared from many MPN and blood cancers labs in York, Sheffield and Cambridge, and was a great day of science with people who like to talk about CALR and MPL and JAK2 as much as we do.

December 5, 2018

ASH 2018

Jeanne, Dom and Edwin headed to sunny California to attend the ASH annual meeting in San Diego. Our work was presented at the Myeloid Workshop and in Oral Abstract sessions by our collaborators from the Dana-Farber Cancer Institute at Harvard Medical School, and Edwin nervously fidgeted with his pen as he chaired the MPN Basic Biology session. Lots of exciting science! 

September 30, 2018

Farewell Rachael!

Sadly, we say farewell to our amazing Research Technician and Twitter-master Rachael who has moved on to join the MedNet Group in Leeds as an Account Executive. She will be doing some incredible and important work in clinical research science communication. She has been a fantastic asset to the lab and will be miss by everyone greatly. Good luck Rachael!

September 20, 2018

Good luck April!

Sadly, the day we've all been dreading is finally here, as our indispensable, irreplaceable, amazing April is finally leaving us to begin her MRC PhD studentship at Newcastle University to work on PNH and bone marrow failure. April was not only a great help to everyone in the lab, but she has been a brilliant and productive scientist in her own right and drove many projects on her own and published a first-author paper in Blood. She will be greatly missed, but we all look forward to the amazing science she will do in her PhD. Good luck April!

July 12, 2018

Congratulations to the Graduating Class of 2018

And a special congratulations to our Y3 Project Students, Nadya and Jack, on their 1st class degrees, (and for keeping our perfect 1st class degrees streak going - we're 5 out of 5!). It was great to have you in the lab.

June 16, 2018

Jeanne receives Travel Award to present her work at EHA Annual Congress

Great news! Jeanne won a European Hematology Association Travel Award for her abstract, which was selected for an oral presentation in the MPN Basic Biology oral session at this year's annual congress in Stockholm. Jeanne did the team proud with a great presentation and received some great feedback. Congratulations to everyone involved in this study - it was a great team effort. 

May 2, 2018

Lab Moves To LC Miall Building

As part of an ambitious £100M refurbishment and modernisation of our faculty infrastructure, the lab was forced to say farewell to our old home on Level 9 of the Garstang Building and moved to fancy new lab space in the LC Miall Building. We won't miss the odd bench layout, the temperature fluctuations in the space and the occasional fly infestation, but it was a good home for over 2 years. Thanks to everyone in the lab and to our faculty technical services team for their hard work in making the move a success, and we are looking forward to collaborating soon and doing some exciting science with our new neighbours in the Zeqiraj, Bayliss, Breeze and Zhuravleva groups 

March 28, 2018

Discovery Zone

Jeanne and Rachael participate in the Discovery Zone, a wonderful event run by postgraduate students as part of the Leeds Festival of Science that aims to provide outreach to young people aged 9-19 to expose them to the wonderful world of science, maths, engineering and technology. Discovery Zone gives Key Stage 2 and 3 pupils the opportunity to try hands-on science in a whistle-stop session of science exploration. Well done to everyone involved!

March 26, 2018

Inaugural FBS-FMH Joint Symposium

We held our inaugural joint symposium celebrating the research activities of the Faculties of Biological Sciences and Medicine & Health. It was a great day of talks and posters which truly reflected the diverse range of bench-to-bedside research activities at Leeds. Thanks to all those who attended.

January 26, 2018

Mini-lab reunion

It's always great when old lab friends visit. Danielle (Y3 project student, class of 2016) and Melina (MSc student, class of 2017) came "home" for a visit, which provided a great excuse for the lab to get some Mexican food!

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January 15, 2018

Erasmus visit

Edwin visited Erasmus Medical Centre in Rotterdam, Netherlands to present some of the lab's recent work on calreticulin. It was a great chance to chat about all things blood with the brilliant haematology division there at Erasmus, and to visit friend of the lab Rebekka Schneider. Thanks to Rebekka and her wonderful lab for the awesome water taxi excursion and for being such great hosts.

December 29, 2017

There will be Blood

Great way to end the year - the lab published its first paper in the journal Blood! April, Danielle and Jeanne worked with investigators at the Brigham and Women's Hospital and Beth Israel Deaconess Hospital at Harvard Medical School to work out how mutant calreticulin binds to the thrombopoietin receptor MPL to drive MPN. Well done to everyone involved!

December 13, 2017

ASH 2017

Our work was selected for an oral presentation at this year's American Society of Hematology annual meeting in Atlanta, and presented by our collaborator Shannon from Ann Mullally's lab. The talk was very well received and we got some great feedback, including a shout-out at the Best of ASH wrap-up. Strong work everyone!

December 11, 2017

Congratulations to this year's cohort of MSc students

Graduation congratulations to Grainne, Melina and Dovile who spent their summers with us for their MSc research projects. Well done all!

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December 2, 2017

Edwin wins the Best Speaker prize at the Taiwan Scientific Symposium in Newcastle

Edwin gave a talk at a research symposium highlighting research from Taiwanese-born scientists in the UK at an interdisciplinary research symposium sponsored by the Science and Technology Division of the Taipei Representative Office in London. It was a great opportunity to listen to some really interesting talks and to make new friends. Thanks to Professor Proty Wu and Yuhua Chen for the invitation and hospitality, and the Newcastle University Taiwanese Society for organising the meeting.

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November 1, 2017

The lab apparates to London to attend the Molecular Haemopoiesis meeting

It was a great day of science with lots of exciting talks from great scientists like Terry Rabbitts, Guy Sauvageau, Martin Pule and many others.

October 1, 2017

Five new people join the lab!

Rachael joins the lab as a Research Technician, Dominic joins as a PhD student funded by a University Research Studentship, and Catherine, Jack and Nadya start their undergraduate projects in the lab. Lab celebrates with brunch! 

July 11 2017

First, first, first...

Many congratulations to Katie, Danielle and Gina who were all awarded with their first class Honours degrees, and also for their exceptional first class Honours projects done in the lab. Well done everyone!

June 5, 2017

Katie passed her Master's viva

Congratulations to Katie who has successfully defended her MBiol research dissertation, and never has to look for Chk1 expression ever again. She will be starting her PhD at the University of Cambridge in October. We'll miss you Katie!

May 16, 2017

Danielle wins third place in poster competition for final year projects

Congratulations to Danielle who won third place for her poster presentation for her final year research project. Way to go! 

December 2, 2016

ASH 2016

The lab escapes dreary Leeds and heads to sunny San Diego for the American Society of Hematology Annual Meeting!

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October 31, 2016

Lab welcomes 5 new people!

In October, we welcomed 5 new people to the lab. Jeanne is funded by the Leeds Anniversary Research Studentship scheme to study her PhD, April joins the lab as a Research Technician, and Danielle, Gina and Katie start their undergraduate projects in the lab. The lab celebrates with obligatory Thai food.  

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May 11, 2016

John Goldman Fellowship

Edwin was awarded the John Goldman Fellowship for Future Science from Leuka to study the role of DNA repair enzymes in the pathogenesis of myelofibrosis (Leuka 2016 John Goldman Fellows). 

April 30, 2016

Two papers published in April

Two new papers were published from the lab in April in Cancer Discovery and Oncogene!

April 12, 2016

Academy of Medical Science Springboard Award

Great news! The lab has been awarded with a Springboard Award from the Academy of Medical Science to study the effects of epigenetic dysregulation in the pathogenesis of primary myelofibrosis. It is a tremendous honour to be a part of the inaugural cohort of awardees. Click here for a write-up from the university.

October 31, 2015

Looking at Life in Molecular Detail

Our research was highlighted in a wonderful article entitled "Looking at Life in Molecular Detail" which discusses the £17M investment into the structural biology infrastucture at the University of Leeds. Exciting times ahead.

© 2019 Edwin Chen

Meeting Marek Michalak, the founder of the Calreticulin Workshop